{"id":5279,"date":"2024-08-22T09:48:43","date_gmt":"2024-08-22T00:48:43","guid":{"rendered":"https:\/\/shinoharashinsha.co.jp\/?page_id=5279"},"modified":"2024-08-26T15:00:47","modified_gmt":"2024-08-26T06:00:47","slug":"%e4%b9%b3%e7%99%8c%e3%81%ae%e8%87%a8%e5%ba%8avol-27-no-3","status":"publish","type":"page","link":"https:\/\/shinoharashinsha.co.jp\/?page_id=5279","title":{"rendered":"\u4e73\u764c\u306e\u81e8\u5e8aVol.27 No.3"},"content":{"rendered":"\n<p><font size=\"7\">\u4e73\u764c\u306e\u81e8\u5e8aVol.27 No.3<\/font><\/p>\n\n\n\n<p><strong>\u76ee\u6b21<br>\u7279\u96c6<br>\u9ad8\u9f62\u8005\u4e73\u764c\uff081\uff09<br>\u5e8f\u6587\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u5c0f\u53e3\u6b63\u5f66\uff08\u304c\u3093\u7814\u7a76\u4f1a\u6709\u660e\u75c5\u9662 \u653e\u5c04\u7dda\u6cbb\u7642\u90e8\uff09\u3000257 (5)<\/strong><\/p>\n\n\n\n<p><strong>\u9ad8\u9f62\u8005\u304c\u3093\u306e\u7279\u6027<\/strong><br><strong>\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u65b0\u4e95\u51a8\u751f\uff08\u6771\u4eac\u90fd\u5065\u5eb7\u9577\u5bff\u533b\u7642\u30bb\u30f3\u30bf\u30fc \u75c5\u7406\u8a3a\u65ad\u79d1\uff09\u30fb\u4ed6\u3000259 (7)<\/strong><\/p>\n\n\n\n<p><strong>\u9ad8\u9f62\u8005\u3092\u7dcf\u5408\u7684\u306b\u6a5f\u80fd\u8a55\u4fa1\u3057\u7406\u89e3\u3057\u652f\u3048\u308b\u533b\u7642\u3068\u30b1\u30a2<br>\u30fc\u30a8\u30f3\u30c9\u30fb\u30aa\u30d6\u30fb\u30e9\u30a4\u30d5\u30b1\u30a2\u30c1\u30fc\u30e0\u306e\u610f\u7fa9\u30fc<br>\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u897f\u5ddd\u6e80\u5247<\/strong><br><strong>\uff08\u56fd\u7acb\u9577\u5bff\u533b\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u75c5\u9662 \u547c\u5438\u5668\u79d1\u30fb\u7de9\u548c\u30b1\u30a2\u79d1\uff09\u30fb\u4ed6\u3000269(17)<\/strong><\/p>\n\n\n\n<p><strong>\u9ad8\u9f62\u8005\u4e73\u764c\u306e\u81e8\u5e8a\u75c5\u7406\u5b66\u7684\u7279\u5fb4<br>\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u672c\u9593\u5c1a\u5b50<\/strong><br><strong>\uff08\u6771\u4eac\u90fd\u5065\u5eb7\u9577\u5bff\u533b\u7642\u30bb\u30f3\u30bf\u30fc\u7814\u7a76\u6240 \u8001\u5e74\u75c5\u7406\u5b66\uff09\u30fb\u4ed6\u3000277(25)<\/strong><\/p>\n\n\n\n<p><strong>\u9ad8\u9f62\u8005\u4e73\u764c\u306e\u5916\u79d1\u7642\u6cd5<\/strong><br><strong>\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u7c73\u5009\u5229\u9999\uff08\u304c\u3093\u7814\u6709\u660e\u75c5\u9662 \u4e73\u817a\u30bb\u30f3\u30bf\u30fc \u4e73\u817a\u5916\u79d1\uff09\u30fb\u4ed6\u3000283(3l)<\/strong><\/p>\n\n\n\n<p><strong>\u8b1b\u5ea7<\/strong><br><strong>\u4e73\u764c\u85ac\u7269\u7642\u6cd5\u306b\u304a\u3051\u308b\u652f\u6301\u7642\u6cd5\u2461<br>\u767a\u71b1\u6027\u597d\u4e2d\u7403\u6e1b\u5c11\u75c7<\/strong><br><strong>\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u6c34\u91ce\u8061\u6717\uff08\u4e09\u91cd\u5927\u5b66\u533b\u5b66\u90e8\u9644\u5c5e\u75c5\u9662 \u816b\u760d\u5185\u79d1\uff09\u3000291 (39)<\/strong><\/p>\n\n\n\n<p><strong>\u539f\u8457<\/strong><br><strong>\u6d78\u6f64\u6027\u5fae\u5c0f\u4e73\u982d\u764c\u6210\u5206\u3092\u6709\u3059\u308b32\u4f8b\u306e\u8d85\u97f3\u6ce2\u753b\u50cf\u306e\u691c\u8a0e<br>\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u52a0\u85e4\u5343\u7d75\u5b50\uff08\u304c\u3093\u7814\u7a76\u4f1a\u6709\u660e\u75c5\u9662 \u8d85\u97f3\u6ce2\u691c\u67fb\u90e8\uff09\u30fb\u4ed6\u3000299(47)<\/strong><\/p>\n\n\n\n<p><strong>\u5f53\u9662\u306b\u304a\u3051\u308b\u4e73\u817a\u30a2\u30dd\u30af\u30ea\u30f3\u764c24\u4f8b\u306e\u691c\u8a0e<\/strong><br><strong>\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u6762\u8c37\u53cb\u9999\u5b50\uff08\u5927\u962a\u52b4\u707d\u75c5\u9662 \u5916\u79d1\uff09\u30fb\u4ed6\u3000307(55)<\/strong><\/p>\n\n\n\n<p><strong>\u85ac\u7269\u7642\u6cd5\u3092\u53d7\u3051\u308b\u4e73\u764c\u60a3\u8005\u306b\u5bfe\u3059\u308b\u751f\u6b96\u6a5f\u80fd\u6e29\u5b58\u76f8\u8ac7\u30b7\u30b9\u30c6\u30e0\u306e\u69cb\u7bc9\u3092\u76ee\u6a19\u3068\u3057\u305f<\/strong><br><strong>\u598a\u5a20\u53ef\u80fd\u671f\u4e73\u764c\u60a3\u8005\u306b\u5bfe\u3059\u308b\u30a2\u30f3\u30b1\u30fc\u30c8\u8abf\u67fb<br>\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u679d\u5712\u5fe0\u5f66\uff08\u5ca1\u5c71\u5927\u5b66\u75c5\u9662 \u4e73\u764c\u6cbb\u7642\u30fb\u518d\u5efa\u30bb\u30f3\u30bf\u30fc\uff09\u30fb\u4ed6\u3000313(61)<\/strong><\/p>\n\n\n\n<p><strong>\u7de8\u96c6\u9867\u554f\uff1d\u83c5\u91ce\u6674\u592b\uff0f\u963f\u90e8\u4ee4\u5f66\uff0f\u59b9\u5c3e\u4e98\u660e\uff0f\u6cc9\u96c4\u52dd\uff0f\u5c0f\u5c71\u535a\u8a18\uff0f\u7530\u5cf6\u77e5\u90ce\uff0f\u5742\u5143\u543e\u5049\uff0f\u971e\u5bcc\u58eb\u96c4\uff0f\u5712\u5c3e\u535a\u53f8<br>\u7de8\u96c6\u59d4\u54e1\uff1d\u79cb\u5c71\u592a**\uff0f\u6c60\u7530\u6b63\uff0f\u4f0a\u85e4\u826f\u5247*\uff0f\u5ca9\u702c\u62d3\u58eb\uff0f\u5c0f\u53e3\u6b63\u5f66\uff0f\u6d25\u5ddd\u6d69\u4e00\u90ce\uff0f\u89d2\u7530\u535a\u5b50\uff0f\u4e2d\u6751\u6e05\u543e**\uff0f\u91ce\u53e3\u771e\u4e09\u90ce\uff0f<\/strong><br><strong>\u5897\u7530\u3057\u306e\u3076<br>*\u7de8\u96c6\u59d4\u54e1\u9577,**\u526f\u7de8\u96c6\u59d4\u54e1\u9577<\/strong><\/p>\n\n\n\n<p><strong>\u4e73\u764c\u306b\u304a\u3051\u308bKi-67\u967d\u6027\u7387\u306e\u8a55\u4fa1\u65b9\u6cd5\uff1a\u753b\u50cf\u89e3\u6790\u88c5\u7f6e\u306b\u3088\u308bKi-67 labeling index\u3068\u75c5\u7406\u533b\u76ee\u8996\u306b\u3088\u308b<\/strong><br><strong>Ki-67\u30b9\u30b3\u30a2\u306e\u6bd4\u8f03\u691c\u8a0e<br>\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u5510\u5c0f\u71d5\uff08\u65e5\u672c\u5927\u5b66\u533b\u5b66\u90e8 \u75c5\u614b\u75c5\u7406\u5b66\u7cfb\u75c5\u7406\u5b66\u5206\u91ce\uff09\u30fb\u4ed6\u3000321 (69)<\/strong><\/p>\n\n\n\n<p><strong>\u30bb\u30f3\u30c1\u30cd\u30eb\u30ea\u30f3\u30d1\u7bc0\u306e\u8853\u4e2d\u8a3a\u65ad\u306b\u304a\u3051\u308bone-step nucleic acid amplification(OSNA) \u6cd5\u306e\u7d4c\u9a13<\/strong><br><strong>\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u4e45\u4fdd\u7530\u535a\u6587\uff08\u798f\u5ca1\u548c\u767d\u75c5\u9662 \u4e73\u817a\u5916\u79d1\uff09\u30fb\u4ed6\u3000327(75)<\/strong><\/p>\n\n\n\n<p><strong>\u75c7\u4f8b<\/strong><br><strong>\u8853\u5f8c18\u5e74\u76ee\u306b\u5168\u8eab\u9aa8\u8ee2\u79fb,\u591a\u767a\u80ba\u8ee2\u79fb\u3092\u304d\u305f\u3057\u305f\u4e73\u764c\u306e1\u75c7\u4f8b<br>\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u7af9\u5185\u5eb8\u6d69(\u5ddd\u5d0e\u75c5\u9662 \u5185\u79d1\uff09\u30fb\u4ed6\u3000333(81)<\/strong><\/p>\n\n\n\n<p><strong>\u8853\u524d\u8a3a\u65ad\u304c\u56f0\u96e3\u3067\u3042\u3063\u305f\u80f8\u7b4b\u6d78\u6f64\u3092\u4f34\u3046\u6d78\u6f64\u6027\u5c0f\u8449\u764c\u306e1\u4f8b<br>\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u9732\u6728\u8302\uff08\u5927\u962a\u8d64\u5341\u5b57\u75c5\u9662 \u4e73\u817a\u4e00\u822c\u5916\u79d1\uff09\u30fb\u4ed6\u3000343 (91)<\/strong><\/p>\n\n\n\n<p><strong>\u4e21\u5074\u6c34\u814e\u75c7,\u5341\u4e8c\u6307\u8178\u9589\u585e\u3092\u5448\u3057\u6025\u901f\u306a\u7d4c\u904e\u3092\u8fbf\u3063\u305f,\u4e73\u764c\u8179\u819c\u30fb\u5f8c\u8179\u819c\u8ee2\u79fb\u306e1\u4f8b<\/strong><br><strong>\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u9ad8\u6d5c\u4f51\u5df1\u5b50\uff08\u90fd\u7acb\u58a8\u6771\u75c5\u9662 \u5916\u79d1\uff09\u30fb\u4ed6\u3000349(97)<\/strong><\/p>\n\n\n\n<p><strong>\u539f\u767a\u6027\u80c3\u764c\u3068\u306e\u9451\u5225\u306b\u82e6\u616e\u3057\u305f\u4e73\u817a\u6d78\u6f64\u6027\u5c0f\u8449\u764c\u80c3\u5358\u72ec\u8ee2\u79fb(T1cN1M1 stage\u2163)\u306e1\u4f8b<\/strong><br><strong>\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u5473\u516b\u6728\u5bff\u5b50\uff08\u5343\u8449\u770c\u304c\u3093\u30bb\u30f3\u30bf\u30fc \u4e73\u817a\u5916\u79d1\uff09\u30fb\u4ed6\u3000353(101)<\/strong><\/p>\n\n\n\n<p><strong>\u8c4a\u80f8\u8853\u5f8c\u30a4\u30f3\u30d7\u30e9\u30f3\u30c8\u5185\u90e8\u306b\u753b\u50cf\u4e0a\u4e73\u982d\u72b6\u75c5\u5909\u3092\u8a8d\u3081\u4e73\u623f\u57cb\u5165\u7570\u7269\u6458\u51fa\u8853\u3092\u65bd\u884c\u3057\u305f\u7121\u83cc\u6027\u816b\u760d\u306e1\u4f8b<br>\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u5ddd\u672c\u4e45\u7d00<\/strong><br><strong>\uff08\u8056\u30de\u30ea\u30a2\u30f3\u30ca\u533b\u79d1\u5927\u5b66 \u30d6\u30ec\u30b9\u30c8\uff06\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u30bb\u30f3\u30bf\u30fc\uff09\u30fb\u4ed6\u3000361 (109)<\/strong><\/p>\n\n\n\n<p><strong>\u30e2\u30fc\u30ba\u8edf\u818f\u51e6\u7f6e\u6642\u306e\u8840\u6e05\u4e9c\u925b\u6fc3\u5ea6\u4e0a\u6607<\/strong><br><strong>\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u5c71\u53e3\u654f\u4e4b\uff08\u5c0f\u8af8\u539a\u751f\u7dcf\u5408\u75c5\u9662 \u5916\u79d1\uff09\u30fb\u4ed6\u3000367(115)<\/strong><\/p>\n\n\n\n<p><strong>\u30a2\u30ca\u30a6\u30f3\u30b9\u30e1\u30f3\u30c8<\/strong><br><strong>\u7b2c4\u56de\u4e73\u817a\u75c5\u7406\u8a3a\u65ad\u7814\u7a76\u4f1a\u30bb\u30df\u30ca\u30fc<\/strong><strong>\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026373(121)<\/strong><\/p>\n\n\n\n<p><a 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